SPR Unknown # 70-- FINAL
Publication Date: 2012-05-16
11-month-old with progressive irritability, crying, and noted increase in head size by family.
CECT shows a large, well defined homogeneously enhancing posterior fossa mass with lobulations and frond-like projections (resulting in a “cauliflower-like” appearance) arising from the right cerebellopontine angle. The mass is compressing the pons, middle cerebellar peduncle and cerebellar hemisphere. There is secondary obstructive hydrocephalus due to compression of the 4th ventricle.
Choroid plexus tumors are derived from choroid plexus epithelium. Tumors of the choroid plexus account for 2%–4% of pediatric brain tumors, and nearly half of these tumors present in the 1st decade of life. Most choroid plexus tumors are benign, choroid plexus papillomas, rather than the much more aggressive choroid plexus carcinomas.
Choroid plexus tumors most commonly occur in the lateral ventricles in children; the cerebellopontine angle is rarely affected. Involvement of the cerebellopontine angle is thought to result from extension of choroid plexus from the 4th ventricle through the lateral foramen of Lushka.
Choroid plexus tumors are associated with hydrocephalus and symptoms related to increased intracranial pressure. In most cases, the hydrocephalus is secondary to an increase in the production of CSF by the tumor. Obstruction of CSF flow from a large or well-placed mass is also a contributing factor in some cases.
- Kumar R, Achari G, Benerji D, Jain VK, Chhabra DK. Choroid plexus papillomas of the cerebellopontine angle. Neurol India 2002;50:352-8.
- Koeller K, Sandberg, G. From the Archives of the AFIP: Cerebral Intraventricular Neoplasms: Radiologic-Pathologic Correlation.RadioGraphics 2002;22,1473-1505