Publication Date: 2006-05-09
Craniosynostosis are generally divided into primary and secondary forms. Primary craniosynostosis refers to premature fusion of one or more cranial sutures, thought to be a developmental anomaly of the skull base. Secondary craniosynostosis refers to premature sutural closure because of other causes such as intrauterine compression of the skull, teratogenic effects or lack of brain growth. Craniosynostosis can be seen in otherwise normal infants or as part of syndromes. Overall, approximately 15% of cases are associated with syndromes.
Of the remaining 85%, 75-80% involved only one suture ("nonsyndromic") where 20-25% are multisuture.
Our case of isolated metopic synostosis (trigonocephaly)comprises about 18%.
- Pediatric Neuroimaging by A. James Barkovich Fourth Edition, 2005. pp 410-414